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Medical Scores – H, I

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Medical Scores – H, I

by Dr.NM Tamilmani
August 19, 2024
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Medical Scores – H


HEPARIN-INDUCED THROMBOCYTOPENIA (HIT):

  • ESTIMATING THE PRE-TEST PROBABILITY OF HIT: THE “FOUR T’S”
Points (0, 1, or 2 for Each of 4 Categories: Maximum Possible Score = 8)
2 1 0
Thrombocytopenia >50% Platelet fall to nadir >/= 20000 30–50% Platelet fall, or nadir 10000-19000 <30% Platelet fall, or nadir <10000
Timing* of onset of platelet fall (or other sequelae of HIT) Days 5–10, or </= day 1 with recent heparin (past 30 days) >Day 10 or timing unclear; or <day 1 with recent heparin

(Past 31–100 days)

<Day 4 (no recent heparin)
Thrombosis or other sequelae Proven new thrombosis; skin necrosis; or acute systemic reaction after intravenous UFH bolus Progressive or recurrent thrombosis; erythematous skin lesions; suspected thrombosis (not proven) None
Other cause(s) of platelet fall None evident Possible Definite
  • UFH, Unfractionated heparin
  • Pre-test probability score: 6–8 indicates high; 4–5, intermediate; and 0–3, low.
  • *First day of immunizing heparin exposure considered day 0.

 


HYPERANDROGENISM:

  • For Female:
    • Ferriman-Gallwey scoring system is used to quantify severity of hirsutism (score of >8 is abnormal for white/black women, >9 abnormal for Mediterranean/Hispanic/Middle-Eastern women, >2 for Asian women)

GI HAEMORRHAGE SCORINGS:

Risk stratification scores for Upper GI haemorrhage
Blatchford score Rockall score
• BUN

• Hb

• BP

• PR

• H/o of Melena, Syncope, Liver or cardiac dysfunction

• Age

• Comorbid diseases

• Magnitude of haemorrhage (Based on BP and PR)

• Transfusion requirement

• Endoscopic findings**

• Stigmata of recent bleed


Medical Scores – I


REVISED ORIGINAL SCORING SYSTEM OF THE INTERNATIONAL AUTOIMMUNE HEPATITIS GROUP

Category Factor Score
Gender Female +2
AlkPhos: AST (or ALT) ratio >3

<1.5

-2

+2

Gamma-globulin or IgG (times

above upper limit of normal)

>2.0

1.5-2.0

1.0-1.5

<1.0

+3

+2

+1

0

ANA, SMA, or anti-LKM1 titers

 

>1:80

1:80

1:40

<1:40

+3

+2

+1

0

AMA Positive -4
Viral markers of active infection Positive

Negative

-3

+3

Hepatotoxic drugs Yes

No

-4

+1

Alcohol <25 g/d

>60 g/d

+2

-2

Concurrent immune disease Any non-hepatic disease of an immune nature +2
Other autoantibodies* Anti-SLA/LP, actin, LC1, pANCA +2

 

Histologic features Interface hepatitis

Plasma cells

Rosettes

None of above

Biliary changes

Atypical features

+3

+1

+1

-5

-3

-3

HLA DR3 or DR4 +1
Treatment response Remission alone

Remission with relapse

+2

+3

Pre-treatment score

Definite diagnosis

Probable diagnosis

Post-treatment score

Definite diagnosis

Probable diagnosis

 

 

 

>15

10-15

 

>17

12-17

Abbreviations: Alkphos- serum alkaline phosphatase level; AST- serum aspartate

aminotransferase level; ALT- serum alanine aminotransferase level; IgG-serum

immunoglobulin G level; AMA- antimitochondrial antibodies; HLA- human leukocyte

antigen.


THE UNRUPTURED INTRACRANIAL ANEURYSM TREATMENT SCORE:

  • Neurology 2015;85(10):881-9
    • Objective: to develop an unruptured intracranial aneurysm (UIA) treatment score (UIATS) model that includes and quantifies key factors involved in clinical decision-making in the management of UIAs and to assess agreement for this model among specialists in UIA management and research.
    • Methods: An international multidisciplinary (neurosurgery, neuroradiology, neurology, clinical epidemiology) group of 69 specialists was convened to develop and validate the UIATS model using a Delphi consensus method.
    • Results: The UIATS accounts for 29 key factors in UIA management.
    • Conclusions: This novel UIA decision guidance study captures an excellent consensus among highly informed individuals on UIA management, irrespective of their underlying specialty.

ICH SCORE COMPONENTS:

  • GCS score (3-4 = 2 pts; 5-12=1 pt, 13-15=0 pt)
  • ICH volume (≥30 cm= 1 pt, <30 cm= 0 pt)
  • Presence of IVH (yes=1 pt, no=0 pt)
  • Infratentorial origin (yes=1 pt, no=0 pt)
  • Age (≥80 = 1 pt, <80 = 0 pt)
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